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czas-i-pomiary: Cousin marriage
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ŹRÓDŁA I DOWODY
3 zapisanych źródełEvidence: 45 • authority: 92
Uncovering the Molecular Signatures of Rare Genetic Diseases in the Punjabi Population.. Rare genetic diseases (RGDs) affect individuals, families, and healthcare systems worldwide. Population-scale genomic data remain largely restricted to Western cohorts with an estimated 10,000 RGDs. South Asian populations remain underrepresented in molecular, clinical, and genomic databases. This study presents the first preliminary molecular genetic characterization of RGDs in the Punjabi population of Pakistan. Data were collected from the provincial RGD registry at the Punjab Thalassemia and Other Genetic Disorders Prevention and Research Institute (PTGDPRI), Lahore. Families diagnosed using next-ge…
Otwórz źródło ↗Evidence: 41 • authority: 92
Ancient genomes reveal an extensive kinship network and endogamy in a Three-Kingdoms period society in Korea.. The burial complex of the Imdang-Joyeong site at Gyeongsan in southeastern Korea is notable for the large number of tombs constructed within ~100 years (fourth and sixth centuries CE) and widespread practice of human sacrifice. Analyzing genome-wide data from 78 individuals, we detected 11, 23, and 20 pairs of the first, second, and three-or-more-distant degree relatives, respectively, revealing a dense network of kinship in the Imdang-Joyeong society. We found five individuals from closely related parents, suggesting the practice of consanguineous marriage in both grave owners and…
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