króliki-i-zające: Tooth

Evidence: 100 • authority: 72

A tooth (pl.: teeth) is a hard, calcified structure found in the jaws (or mouths) of many vertebrates and are used to break down food. Some animals, particularly carnivores and omnivores, also use teeth to help with capturing or wounding prey, tearing food, for defensive purposes, to intimidate other animals often including their own, or to carry prey or their young. The roots of teeth are covered by gums. Teeth are not made of bone, but rather of multiple tissues of varying density and hardness that originate from the outermost embryonic germ layer, the ectoderm. The general structure of teeth is similar across the vertebrates, although there is considerable variation in their form and pos…

Evidence: 79 • authority: 72

Evidence: 59 • authority: 72

Evidence: 45 • authority: 90

Evidence: 45 • authority: 72

Evidence: 45 • authority: 72

Evidence: 38 • authority: 80

Why Mammals Grow Teeth Only Twice: Implications for the Safety and Ethics of Tooth-Regeneration Drugs Author

Evidence: 38 • authority: 80

The variation in eruption of permanent teeth and loss of deciduous teeth in Western Australian children

Evidence: 38 • authority: 90

Evidence: 38 • authority: 92

Evidence: 38 • authority: 92

Development of tooth regenerative medicine strategies by controlling the number of teeth using targeted molecular therapy.. Analysis of various genetically modified mice, with supernumerary teeth, has revealed the following two intrinsic molecular mechanisms that increase the number of teeth. One plausible explanation for supernumerary tooth formation is the rescue of tooth rudiments. Topical application of candidate molecules could lead to whole tooth formation under suitable conditions. Congenital tooth agenesis is caused by the cessation of tooth development due to the deletion of the causative gene and suppression of its function. The arrest of tooth development in Runx2 knockout mice,…

Evidence: 38 • authority: 92

Count Me in, Count Me out: Regulation of the Tooth Number via Three Directional Developmental Patterns.. Tooth number anomalies, including hyperdontia and hypodontia, are common congenital dental problems in the dental clinic. The precise number of teeth in a dentition is essential for proper speech, mastication, and aesthetics. Teeth are ectodermal organs that develop from the interaction of a thickened epithelium (dental placode) with the neural-crest-derived ectomesenchyme. There is extensive histological, molecular, and genetic evidence regarding how the tooth number is regulated in this serial process, but there is currently no universal classification for tooth number abnormalities. I…