Pies: Dogs are naturally submissive to any creature with higher pack status, human or canine

Evidence: 60 • authority: 88

Evaluation of coagulation status in dogs with naturally occurring canine hyperadrenocorticism. Abstract Objective To determine whether or not there are differences in coagulation parameters (eg, thrombelastography [ TEG ], activated partial thromboplastin time [a PTT ], prothrombin time [ PT ], and fibrinogen) among dogs with naturally occurring hyperadrenocorticism ( HAC ), dogs with HAC undergoing medical management, and dogs without HAC . Design Prospective, observational study. Setting Veterinary teaching hospital. Animals Forty‐six client‐owned dogs undergoing adrenal function testing. Interventions None. Measurements and Main Results Nine dogs were diagnosed with HAC de novo, 19 dogs…

Evidence: 52 • authority: 88

Canine Pancreatic-Specific Lipase Concentrations in Clinically Healthy Dogs and Dogs with Naturally Occurring Hyperadrenocorticism. Abstract Background Specificity of canine pancreatic lipase immunoreactivity (cPLI) assays in dogs with hyperadrenocorticism (HAC) is unknown. Hypothesis Results of cPLI assays differ for clinically healthy dogs and dogs with HAC. Animals Seventeen healthy dogs and 20 dogs with HAC diagnosed by ACTH stimulation test results without evidence of clinical pancreatitis. Methods Dogs were enrolled between December 2009 and November 2010. Serum cPLI concentrations were determined by quantitative (Spec cPL test, SPEC) and semiquantitative (SNAP cPL test, SNAP) assays.…

Evidence: 43 • authority: 88

Immunohistochemical, Immunofluorescent, and Molecular Investigation of Canine Distemper Virus, Nectin 4, and CD150 Receptors in Naturally Infected Dogs with Canine Distemper Virus. Canine distemper virus uses CD150 and Nectin-4 receptors to infect cells. In the central nervous system, astrocytes, the main canine distemper virus target, reportedly lack these receptors, suggesting alternative entry pathways. This study investigated canine distemper virus distribution and receptor usage in naturally infected dogs’ organs and tissues using immunohistochemistry and immunofluorescence. Tissue samples from 34 dogs (including the central nervous system, internal organs, footpads, and planum nasale)…

Evidence: 43 • authority: 88

Co-expression of nectin-4 receptor and canine distemper viral antigen in naturally infected dogs. Canine distemper virus (CDV) is a virulent infected virus which threatens many mammalian species rendering multisystemic symptoms. The crucial cellular receptor for this virus is signaling lymphocyte activation molecule (SLAM) which expressed on immune cells. It can infect in silencing SLAM expression cells including epithelium and central nervous system. The newly cellular receptor for Measles virus (MV), the closely related morbillivirus, has been investigated so-called nectin-4 receptor. The aims of this study were to investigate the distribution of nectin-4 receptor in canine tissues and to…

Evidence: 43 • authority: 92

Neophilia in wolves and dogs.. The study of domestication provides a unique opportunity to analyze the effects of natural selection in the attraction towards novelty, because selective pressures on domesticated animals are often greatly diminished or different from their wild counterparts. In this study, we investigated the neophilic levels of three groups of canids differing in their level of contact with human environments both from an evolutionary and ontogenetic perspective: wolves, pack-living dogs, and pet dogs. In order to study their neophilic response, we presented the animals with two objects. The first of these objects was displayed in the animals' enclosure for several days. Aft…

Evidence: 43 • authority: 92

Monitoring the health of wolves (Canis lupus): Integrating conservation and public health.. The grey wolf (Canis lupus) population is expanding in parts of Europe due to legal protection and favorable ecological conditions. As wolves increasingly move into urban and suburban areas, interactions with domestic dogs become more frequent, raising the risk of pathogen transmission and posing potential threats to both wolf conservation and public health. This study investigated the health status of wolves in the Foreste Casentinesi National Park (Italy) using non-invasive fecal sampling conducted between May 2019 and March 2020. Samples were genetically analyzed to identify individuals and then s…

Evidence: — • authority: 38