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Ciekawostka: Your stomach produces a new layer of mucus every two weeks so that it doesn’t digest itself
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3 zapisanych źródełEvidence: 42 • authority: 92
Physical, chemical, and structural properties of human gastric organoid-derived mucus.. The gastric mucus layer protects the epithelium from gastric acid and ingested pathogens. However, studies of human gastric mucus have been limited due to poor accessibility of native human mucus and the abundance of contaminants in these samples. Here, we explored the potential of human gastric organoids as models for mucus production. Immunofluorescence staining confirmed that the organoids produced mucus containing MUC5AC and MUC6. The luminal mucus had viscoelastic properties similar to those of native human gastric mucus, as determined by particle tracking microrheology. To collect organoid-produced…
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