BANK • PEŁNY PODGLĄD
język: Orthographies and dyslexia
Fakty • wikipedia-seeded
ŹRÓDŁA I DOWODY
4 zapisanych źródełEvidence: 59 • authority: 92
Whole-exome sequencing in children with dyslexia implicates rare variants in CLDN3 and ion channel genes.. Dyslexia is a specific difficulty in learning to read that affects 5-10% of school-aged children and is strongly influenced by genetic factors. While previous studies have identified common genetic variants associated with dyslexia, the role of rare variants has only recently begun to emerge from pedigree studies and has yet to be systematically tested in larger cohorts. Here, we present a whole-exome sequencing (WES) study of 53 individuals with dyslexia, followed by an analysis in 38 cases with reading difficulties and 82 controls assessed with reading measures. Of the 22 genes that…
Otwórz źródło ↗Evidence: 49 • authority: 92
Gene-Environment Interplay in Reading Performance.. Genetic factors are known to play a role in shaping reading abilities and their underlying cognitive processes. However, understanding how genetic and environmental factors interact to influence reading outcomes remains largely unknown. By evaluating the interplay between genetic and environmental influences on reading performance, this study aims to provide insights into the complex mechanisms underlying reading abilities. To this aim, we leveraged the Adolescent Brain Cognitive Development dataset, considering socioeconomic indicators including household income and parental education, along with linguistic characteristics such as bilingu…
Otwórz źródło ↗Evidence: 49 • authority: 72
The genetic mechanism of synesthesia has long been debated, with researchers previously claiming it was a single X-linked trait due to seemingly higher prevalence in women and no evidence of male-male transmission This is where the only synesthetic parent is male and the male child has synesthesia, meaning that the trait cannot be solely linked to the X chromosome. The Mendelian nature of the trait was further disproven when case studies showed that the Phenotype of synesthesia could be differentially expressed in monozygotic (genotypically identical) twins While both twins had the same genome with the potential for phenotypic expression of synesthesia, only one had documented synesthesia.…
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