medycyna-historyczna: Henrietta Lacks

Evidence: 100 • authority: 72

Henrietta Lacks (née Loretta Pleasant; August 1, 1920 – October 4, 1951) was an African-American woman whose cancer cells are the source of the HeLa cell line, the first immortalized human cell line and one of the most important cell lines in medical research. An immortalized cell line reproduces indefinitely under specific conditions, and the HeLa cell line continues to be a source of invaluable medical data and research to the present day. Lacks was the unwitting source of these cells from a tumor biopsied during her treatment for cervical cancer at the Johns Hopkins Hospital in Baltimore, Maryland, in 1951. These cells were then cultured by George Otto Gey, who created the cell line know…

Evidence: 66 • authority: 72

HeLa () is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. HeLa cells are durable and prolific, allowing for extensive applications in scientific study. The line is derived from cervical cancer cells taken without consent on February 8, 1951, from Henrietta Lacks, a 31-year-old African-American woman, after whom the line is named. Lacks died of cancer on October 4, 1951. The cells from Lacks's cancerous cervical tumor were taken without her knowledge, which was common practice in the United States at the time. Cell biologist George Otto Gey found that they could be kept alive, and developed a cell line. Previously, c…

Evidence: 51 • authority: 88

Who would own the HeLa cell line if the Henrietta Lacks case happened in present-day South Africa?. Abstract The HeLa cell line was created in 1951 without consent from Henrietta Lacks, the person whose tissue sample was used. In 2021, the descendants of Henrietta Lacks sued a well-known biotechnology company for the profits it made from the HeLa cell line. In this article, ownership of the cell lines is investigated from a South African legal perspective by considering three possible contemporary scenarios bearing points of similarity to the Henrietta Lacks case. In the first scenario, informed consent is obtained to use a tissue sample for research and to commercialize the products of suc…

Evidence: 31 • authority: 80

Record of the first physician to see Henrietta Lacks at the Johns Hopkins Hospital: History of the beginning of the HeLa cell line

Evidence: 31 • authority: 72

Evidence: 31 • authority: 72

The Immortal Life of Henrietta Lacks is a 2017 American drama television film directed by George C. Wolfe and starring Oprah Winfrey and Rose Byrne. It is based on the book of the same name by Rebecca Skloot and documents the story of Henrietta Lacks, who was diagnosed with cervical cancer in the 1950s, and whose cancer cells (later known as HeLa) would change the course of cancer treatment. The film premiered on HBO on April 22, 2017.

Evidence: 31 • authority: 72

An immortalised cell line is a population of cells from a multicellular organism that would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur naturally or be intentionally induced for experimental purposes. Immortal cell lines are a very important tool for research into the biochemistry and cell biology of multicellular organisms. Immortalised cell lines have also found uses in biotechnology. An immortalised cell line should not be confused with stem cells, which can also divide indefinite…